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Berberine May Have a Positive Effect for Diabetes Patients

Since 2008, there has been an avalanche of scientific research being published on the botanical extract called berberine. It has many properties, but the one most recently in the news is its effects on type 2 diabetes. Dramatic results have been seen with type 2 diabetes patients, including significant reductions in key markers related to glucose control such as hemoglobin A1c (dropped from 9.5% to 7.5%), fasting insulin, fasting blood sugars (dropped from 191 to 124), blood sugars (dropped from 356-199) and insulin levels after eating, a measurement of insulin resistance (HOMA-IR), and systolic blood pressure, triglycerides (dropped from 99 to 78), total cholesterol and LDL cholesterol. The researchers reported it was safe and well tolerated. 

Another research study done in 2008 reported that berberine exhibited an identical effect to metformin in the regulation of blood sugar and was better than metformin in the regulation of lipid metabolism (triglycerides and cholesterol). It has also been shown to improve or even reverse the signs and symptoms of metabolic syndrome, the precursor to type 2 diabetes. Insulin resistance dropped by 45% in one study. These studies were all controlled, which means that they compared berberine to placebo or currently prescribed medications for type 2 diabetes, and all proved berberine to be clinically effective. Of course, there are many other natural therapies which can also be used to regulate and even normalize blood sugar in type 2 diabetes, including diet, exercise, vitamins and minerals.

Advance Health carries Douglas Labs product called Berberine Balance. Each capsule contains berberine 500 mg, alpha-lipoic acid 50 mg and grape seed extract 50 mg. Grape seed is an antioxidant and alpha-lipoic acid helps to support proper insulin function. The dose of berberine that has been used and is effective is 500 mg 3 times daily.